STOCK Tg(Mbp-PDGFB)90Ubc/Kieg
| Status | Available to order |
| EMMA ID | EM:00134 |
| Citation information | RRID:IMSR_EM:00134 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tg(Mbp-PDGFB)90Ubc/Kieg |
| Alternative name | MBP-PDGF B, MBP-PDGFB |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Mbp-PDGFB)90Ubc |
| Gene/Transgene symbol | Tg(Mbp-PDGFB)90Ubc |
Information from provider
| Provider | Karin Forsberg-Nilsson |
| Provider affiliation | Department of Medical Biochemistry and Microbiology, Department of Medical Biochemistry and Microbiology |
| Phenotypic information | Homozygous mice breed poorly. Increase in number of oligodendrocytes and astrocytes in white matter tracts that seem to normalize in adult life. Disorganized retinal cell layers, disorganized retinal capillary network. |
| References |
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Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF-B in myelinating tracts.;Forsberg-Nilsson Karin, Erlandsson Anna, Zhang Xiao-Qun, Ueda Hideho, Svensson Kristian, Nistér Monica, Trapp Bruce D, Peterson Alan C, Westermark Bengt, ;2003;Glia;41;276-89; 12528182