C57BL/6-Tg(H2-Dd/H2-Ld)DL1Ul/Kctt
| Status | Available to order |
| EMMA ID | EM:01366 |
| Citation information | RRID:IMSR_EM:01366 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Tg(H2-Dd/H2-Ld)DL1Ul/Kctt |
| Alternative name | C.B6-Tg(H2Dd alfa1/H2Dd alfa2/H2Dd alfa3)DL1 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(H2-Dd/H2-Ld)DL1Ul |
| Gene/Transgene symbol | Tg(H2-Dd/H2-Ld)DL1Ul |
Information from provider
| Provider | Petter HOGLUND |
| Provider affiliation | MTC, Karolinska Instituet |
| Genetic information | MHC class I gene construct containing the alpha1/alpha2 domain sequences from H2-Dd, coupled to the alpha3 and intracellular domain sequences from H2-Ld. |
| Phenotypic information | No defects known. |
| Breeding history | Transgenic on C57BL/6J background. Brother x sister inbreeding. |
| References |
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Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets. Protection mediated by alpha 1/alpha 2 domains.;Sentman C L, Olsson M Y, Salcedo M, Höglund P, Lendahl U, Käre K, ;1994;Journal of immunology (Baltimore, Md. : 1950);153;5482-90; 7989750