MGI phenotypes (gene matching)
B6.129-Prss16tm1.1Mal/Orl
| Status | Available to order |
| EMMA ID | EM:01380 |
| Citation information | RRID:IMSR_EM:01380 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-Prss16tm1.1Mal/Orl |
| Alternative name | Prss 16 KO B6 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Prss16tm1.1Mal |
| Gene/Transgene symbol | Prss16 |
Information from provider
| Provider | Alice Carrier |
| Provider affiliation | Inserm U624 |
| Genetic information | Knock-out mutation of the Prss16 (Tssp) gene, specifically expressed in the thymus. |
| Phenotypic information | Minor problems in the development of thymus. |
| Breeding history | Backcrosses=8, Intercrosses=4. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
Literature references
- Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes.;Gommeaux Julien, Grégoire Claude, Nguessan Prudence, Richelme Mireille, Malissen Marie, Guerder Sylvie, Malissen Bernard, Carrier Alice, ;2009;European journal of immunology;39;956-64; 19283781