B6.Cg-Dmrt3tm1Hgc/Kctt
| Status | Available to order |
| EMMA ID | EM:13800 |
| Citation information | RRID:IMSR_EM:13800 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Dmrt3tm1Hgc/Kctt |
| Alternative name | Dmrt3 KO |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Dmrt3tm1Hgc |
| Gene/Transgene symbol | Dmrt3 |
Information from provider
| Provider | Nadav Ahituv |
| Provider affiliation | Department of Bioengineering and Therapeutic Sciences, Institute for Human Genetics UCSF |
| Genetic information | Knockout of Dmrt3 gene by homologous recombination in ES cells. |
| Phenotypic information | Homozygous:Not viableHeterozygous:No phenotype |
| Breeding history | 7 generations on C57BL/6 |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- Deletion of ultraconserved elements yields viable mice.;Ahituv Nadav, Zhu Yiwen, Visel Axel, Holt Amy, Afzal Veena, Pennacchio Len A, Rubin Edward M, ;2007;PLoS biology;5;e234; 17803355
- Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice.;Andersson Lisa S, Larhammar Martin, Memic Fatima, Wootz Hanna, Schwochow Doreen, Rubin Carl-Johan, Patra Kalicharan, Arnason Thorvaldur, Wellbring Lisbeth, Hjälm Göran, Imsland Freyja, Petersen Jessica L, McCue Molly E, Mickelson James R, Cothran Gus, Ahituv Nadav, Roepstorff Lars, Mikko Sofia, Vallstedt Anna, Lindgren Gabriella, Andersson Leif, Kullander Klas, ;2012;Nature;488;642-6; 22932389