NOD.B6-(D1Mit113-D1Mit359)/GhjOrl
| Status | Available to order |
| EMMA ID | EM:01397 |
| Citation information | RRID:IMSR_EM:01397 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | NOD.B6-(D1Mit113-D1Mit359)/GhjOrl |
| Alternative name | NOD.B6-C1D(L6) |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Nktcn1C57BL/6J |
| Gene/Transgene symbol | Nktcn1 |
Information from provider
| Provider | Henri-Jean Garchon |
| Provider affiliation | ER70 CNRS et Unite 125 Inserm |
| Genetic information | NOD congenic strain with the distal chromosome 1 from C57BL/6. Line 6 has a smaller interval than L2 and has lost the Fcgr2 locus from C57BL/6. |
| Phenotypic information | This line has lost the main QTL controlling serum levels of IgG1 and IgG2b in NOD mice and present in L2 mice. The L6 interval also controls the severity of experimental arthritis, the number and the function of natural killer T cells, IgE serum levels, and an increased resistance to endotoxinic shock. |
| Breeding history | 20 generations of backcrosses followed by sister-brother matings. Selection of subcongenics by additional backcrosses. |
| References | None available |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |