| Status | Available to order |
| EMMA ID | EM:14889 |
| Citation information | RRID:IMSR_EM:14889 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Dhx15em2Mmru/Cnbc |
| Alternative name | C57BL/6 Dhx15 knockout |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Dhx15em2Mmru |
| Gene/Transgene symbol | Dhx15 |
| Provider | Manuel Morales |
| Provider affiliation | Biochemistry and molecular genetics, Hospital Clinic |
| Genetic information | This strain was generated by creating a Dhx15 knock-out in C57BL/6 mice by microinjection of TALENs in fertilized eggs. The Dhx15 gene (GeneBank accession number: NM_007839.3; Ensembl: ENSMUSG00000029169) is located on mouse chromosome 5. Fourteen exons have been identified, with the ATG start codon in exon 1 and the TGA stop codon in exon 14. Exon 2 was selected as TALEN target site. |
| Phenotypic information | Homozygous:Homozygous mice are not viable.Heterozygous:No phenotype observed. |
| Breeding history | Founders (F0): C57BL/6 x C57BL/6 (WT) Founders (F1): C57BL/6 x C57BL/6 (WT) |
| References |
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| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
