FVB/N-Tg(Slc12a5-luc)#Msa/Oulu
| Status | Available to order |
| EMMA ID | EM:14927 |
| Citation information | RRID:IMSR_EM:14927 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB/N-Tg(Slc12a5-luc)#Msa/Oulu |
| Alternative name | Intron-luc KCC2(6.8)Luc |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Slc12a5-luc)#Msa |
| Gene/Transgene symbol | Tg(Slc12a5-luc)#Msa |
Information from provider
| Provider | Matti Airaksinen |
| Provider affiliation | Univ Helsinki |
| Genetic information | The KCC2(6.8)luc is a transgenic luciferase reporter line with a genomic fragment of the Slc12a5 (KCC2) gene: 6.8 kb Slc12a5 promoter-intron genomic sequence fused to the luciferase reporter. |
| Phenotypic information | Homozygous:NormalHeterozygous:Normal |
| Breeding history | The transgenic mice were produced by standard DNA pronucleus injection of fertilized FVB/N mouse oocytes. The transgenic strain was maintained in this background and has no obvious phenotype. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Oulu, Oulu, Finland |
| Animals used for archiving | heterozygous FVB/N males |
Literature references
- Neuronal K+/Cl- co-transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone-specific expression and developmental up-regulation of endogenous KCC2 gene.;Uvarov Pavel, Pruunsild Priit, Timmusk Tõnis, Airaksinen Matti S, ;2005;Journal of neurochemistry;95;1144-55; 16271048