B6.Cg-Tg(Hnrnpa2b1-SLC25A46)5585Edou/Flmg
| Status | Available to order |
| EMMA ID | EM:15303 |
| Citation information | RRID:IMSR_EM:15303 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Hnrnpa2b1-SLC25A46)5585Edou/Flmg |
| Alternative name | B6-Tg(SLC25A46)5585Edou/Flmg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(hnRNPA2B1/CBX3-SLC25A46)5585Edou |
| Gene/Transgene symbol | Tg(Hnrnpa2b1-SLC25A46)5585Edou |
Information from provider
| Provider | Eleni Douni |
| Provider affiliation | BioInnovation, B.S.R.C. "Alexander Fleming" |
| Genetic information | SLC25A46 cDNA tagged with the Flag epitope at the C-terminus was inserted in the mouse genome under the control of the CBX3/hnRNPA2 promoter. The gene cassette also consists of a Kozak sequence before the human SLC25A46 cDNA and the 3' untranslated region of the human beta-globin gene at the end. Around 30 copies of the transgene. |
| Phenotypic information | Homozygous:NormalHeterozygous:The progenies of this line have a mild growth retardation, but their phenotype seems normal during adulthood. |
| Breeding history | 8th generation of transgenic mice backcrossed to the C57BL/6 background. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | heterozygous males |
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