C3H.C-Zfhx3Sci/H
| Status | Available to order |
| EMMA ID | EM:00156 |
| Citation information | RRID:IMSR_EM:00156 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3H.C-Zfhx3Sci/H |
| Alternative name | PLAY8 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Zfhx3Sci |
| Gene/Transgene symbol | Zfhx3 |
Information from provider
| Provider | Pat Nolan |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Genetic information | Mice carrying this mutation are small in size, exhibit muscle wasting and muscular dystrophy. Mice homozygous for this mutation show tremors when by the tail. |
| Phenotypic information | Mice carrying this mutation have a short circadian period of wheel-running activity (22.5 h rather than 23.5 h). |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (allele matching)
MGI phenotypes (gene matching)
- decreased body weight / MGI
- decreased body size / MGI
- hypoactivity / MGI
- abnormal eating behavior / MGI
- premature death / MGI
- abnormal fertility/fecundity / MGI
- no abnormal phenotype detected / MGI
- decreased thyroid-stimulating hormone level / MGI
- decreased growth hormone level / MGI
- endocrine/exocrine gland phenotype / MGI
- postnatal lethality, incomplete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- abnormal circadian behavior / MGI
- shortened circadian behavior period / MGI
- arrhythmic circadian behavior persistence / MGI
- abnormal circadian behavior phase / MGI
- advanced circadian behavior phase / MGI
- abnormal circardian behavior entrainment / MGI
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191
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