C3H.C-Zfhx3Sci/H

Status

Available to order

EMMA IDEM:00156
Citation informationRRID:IMSR_EM:00156 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameC3H.C-Zfhx3Sci/H
Alternative namePLAY8
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolZfhx3Sci
Gene/Transgene symbolZfhx3

Information from provider

ProviderPat Nolan
Provider affiliationMRC Mammalian Genetics Unit
Genetic informationMice carrying this mutation are small in size, exhibit muscle wasting and muscular dystrophy. Mice homozygous for this mutation show tremors when by the tail.
Phenotypic informationMice carrying this mutation have a short circadian period of wheel-running activity (22.5 h rather than 23.5 h).
References
  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal circadian behavior / MGI
  • shortened circadian behavior period / MGI
  • arrhythmic circadian behavior persistence / MGI
  • abnormal circadian behavior phase / MGI
  • advanced circadian behavior phase / MGI
  • abnormal circardian behavior entrainment / MGI
  • prenatal lethality, complete penetrance / MGI
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • decreased body size / MGI
  • hypoactivity / MGI
  • abnormal eating behavior / MGI
  • premature death / MGI
  • abnormal fertility/fecundity / MGI
  • no abnormal phenotype detected / MGI
  • decreased thyroid-stimulating hormone level / MGI
  • decreased growth hormone level / MGI
  • endocrine/exocrine gland phenotype / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • abnormal circadian behavior / MGI
  • shortened circadian behavior period / MGI
  • arrhythmic circadian behavior persistence / MGI
  • abnormal circadian behavior phase / MGI
  • advanced circadian behavior phase / MGI
  • abnormal circardian behavior entrainment / MGI

Literature references

  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).