129S5;129P2-Baiap2Gt(XN660)Byg/WtsiH

Status

Available to order

EMMA IDEM:15870
Citation informationRRID:IMSR_EM:15870 

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International strain name129S5;129P2-Baiap2Gt(XN660)Byg/WtsiH
Alternative name129-Baiap2/H
Strain typeGene-trap
Allele/Transgene symbolBaiap2Gt(XN660)Byg
Gene/Transgene symbolBaiap2

Information from provider

ProviderSeth Grant
Provider affiliationWellcome Trust Sanger Institute
Genetic informationInformation sourced from Supplementary Data 1 for https://doi.org/10.1101/500389: The mice were created using mouse embryonic stem (ES) cell line (XN660, strain 129/Ola) with an insertional mutation in Baiap2 carrying insertional mutation in XN660 by the gene-trapping vector, pGT1lxf, that was designed to create an in-frame fusion between the 5' exons of the trapped gene and a reporter Thus, the gene-trapped locus is predicted to yield a fusion transcript containing exons 1-10 of Baiap2.
Phenotypic informationMutant mice showed large overall behavioural difference from wildtypes. These included innate/instinctive behaviour, and learning and memory
Breeding historyMice were maintained by backcrossing onto the 129S5/SvEvBrd background; heterozygous males and females were fertile and used to set up intercrosses to generate
ReferencesNone available
Homozygous fertilenot known
Homozygous viableyes
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • decreased circulating calcium level / IMPC
  • abnormal testis morphology / IMPC
  • thrombocytopenia / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • edema / IMPC
  • small testis / IMPC

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Genotyping protocol

Example health report
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