C57BL/6J-Per2^tm1Jt/H

Status	Available to order
EMMA ID	EM:15879
Citation information	RRID:IMSR_EM:15879 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6J-Per2^tm1Jt/H
Alternative name	C57BL/6J-Per2/H
Strain type	Targeted Mutant Strains
Allele/Transgene symbol	Per2^tm1Tj
Gene/Transgene symbol	Per2

Information from provider

Provider	Joseph Takahashi
Provider affiliation	Northwestern University
Genetic information	Information sourced from: PMID: 14963227: This strain carries a firefly Luc gene fused to the terminal exon of the endogenous mPer2 locus by means of homologous recombination in ES cells to create a fusion protein reporter. This reporter line can be used to determine circadian molecular oscillations in vitro in tissue explants and dissociated cells.
Phenotypic information	Homozygous: Phenotype information available on MGI and PMID:14963227 Heterozygous: Phenotype information available on MGI and PMID:14963227
Breeding history	Targeted 129SvEvTac ES cells were injected into C57BL/6J blastocysts and transferred to pseudopregnant C57BL/6J female recipients. . Backcrossed to C57BL/6J for atleast five generations.
References	PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.;Yoo Seung-Hee, Yamazaki Shin, Lowrey Phillip L, Shimomura Kazuhiro, Ko Caroline H, Buhr Ethan D, Siepka Sandra M, Hong Hee-Kyung, Oh Won Jun, Yoo Ook Joon, Menaker Michael, Takahashi Joseph S, ;2004;Proceedings of the National Academy of Sciences of the United States of America;101;5339-46; 14963227
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	not known

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Literature references

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.;Yoo Seung-Hee, Yamazaki Shin, Lowrey Phillip L, Shimomura Kazuhiro, Ko Caroline H, Buhr Ethan D, Siepka Sandra M, Hong Hee-Kyung, Oh Won Jun, Yoo Ook Joon, Menaker Michael, Takahashi Joseph S, ;2004;Proceedings of the National Academy of Sciences of the United States of America;101;5339-46; 14963227

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

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C57BL/6J-Per2tm1Jt/H