IMPC phenotypes (gene matching)
B6N(Cg)-Tspan8tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:15886 |
| Citation information | RRID:IMSR_EM:15886 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N(Cg)-Tspan8tm1.1Ics/Ics |
| Alternative name | K656 |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Tspan8tm1.1Ics |
| Gene/Transgene symbol | Tspan8 |
Information from provider
| Provider | Claude Boucheix |
| Provider affiliation | UMR-S 1197, SFR André Lwoff, INSERM |
| Genetic information | A loxP site was inserted upstream of exon 1 (ENSMUSE00000963885, Tspan8-203). An FRT-flanked Neo cassette followed by a 3' loxP site were inserted downstream of exon 2 (ENSMUSE00000476389). The neo cassette was removed by flp-mediated recombination using the flp deleter mouse line (MGI:2158498) and left exon 1 and exon 2 floxed. |
| Phenotypic information | Homozygous:N/AHeterozygous:No phenotype observed |
| Breeding history | BD10 ES cells. Pure C57BL/6N genetic background. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Literature references
- The Tetraspanin Tspan8 Associates with Endothelin Converting Enzyme ECE1 and Regulates Its Activity.;Zhu Yingying, Saint-Pol Julien, Nguyen Viet, Rubinstein Eric, Boucheix Claude, Greco Céline, ;2023;Cancers;15;; 37835445