B6N(Cg)-Wdr5tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:15892 |
| Citation information | RRID:IMSR_EM:15892 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N(Cg)-Wdr5tm1.1Ics/Ics |
| Alternative name | K580 |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Wdr5tm1.1Ics |
| Gene/Transgene symbol | Wdr5 |
Information from provider
| Provider | Jean-Luc Plassat |
| Provider affiliation | |
| Genetic information | A loxP site was inserted upstream of exon 2 (ENSMUSE00000769379; GRCm39, Wdr5-201). An FRT-flanked Neo cassette followed by a 3' loxP site was inserted downstream of exon 4 (ENSMUSE00001206138). The neo cassette was removed by flp-mediated recombination using our flp deleter mouse line (MGI:2158498) and left exon 2, exon 3 and exon 4 floxed. For additional information, please have a look at this report. |
| Phenotypic information | Homozygous:N/AHeterozygous:No phenotype observed |
| Breeding history | TB1 ES cells; pure C57BL/6N genetic background. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Literature references
- The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry.;Vilhais-Neto Gonçalo C, Fournier Marjorie, Plassat Jean-Luc, Sardiu Mihaela E, Saraf Anita, Garnier Jean-Marie, Maruhashi Mitsuji, Florens Laurence, Washburn Michael P, Pourquié Olivier, ;2017;Nature communications;8;728; 28959017