IMPC phenotypes (gene matching)
B6N(Cg)-H2az1tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:15893 |
| Citation information | RRID:IMSR_EM:15893 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N(Cg)-H2az1tm1.1Ics/Ics |
| Alternative name | K401(b) |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | H2az1tm1.1Ics |
| Gene/Transgene symbol | H2az1 |
Information from provider
| Provider | Stefan Dimitrov |
| Provider affiliation | Institute for Advanced Biosciences, Inserm U 1209, CNRS UMR 5309, Université Grenoble Alpes |
| Genetic information | A loxP site was inserted upstream of exon 2 (H2az1-201, ENSMUSE00001255094). A 3' loxP followed by an FRT-flanked Neo cassette was inserted downstream of exon 4 (ENSMUSE00001260075). The neo cassette was removed by flp-mediated recombination using a FlpE deleter mouse line (MGI:2158498) and left exon 2, exon 3 and exon 4 floxed. For additional information, please have a look at this report. |
| Phenotypic information | Homozygous:N/AHeterozygous:No phenotype observed |
| Breeding history | P1 ES cells. The line was backcrossed 3 times with C57BL/6N mice (currently maintained background: C57BL/6N 84.3875%, 129/SvPas 12.5%, C57BL/6J 3.1125%). |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Literature references
- H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.;Belotti Edwige, Lacoste Nicolas, Simonet Thomas, Papin Christophe, Padmanabhan Kiran, Scionti Isabella, Gangloff Yann-Gaël, Ramos Lorrie, Dalkara Defne, Hamiche Ali, Dimitrov Stefan, Schaeffer Laurent, ;2020;Nucleic acids research;48;4601-4613; 32266374