| Status | Available to order |
| EMMA ID | EM:16009 |
| Citation information | RRID:IMSR_EM:16009 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3H/HeH.C57BL/6J-Pde6b+Pcsk1mpc242H/H |
| Alternative name | C3H/HeH.C57BL/6J-Pde6b<+>Pcsk1 |
| Strain type | Induced Mutant Strains |
| Allele/Transgene symbol | Pcsk1mpc242H |
| Gene/Transgene symbol | Pcsk1 |
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This strain carries a G to T point mutation that results in the amino acid substitution of leucine for valine at position 96 in Pcsk1. Homozygous mice display hyperproinsulinemia and early-onset obesity phenotype. |
| Phenotypic information | Homozygous mice display hyperproinsulinemia and early-onset obesity phenotype. |
| Breeding history | MUTA-G1-C3PDE/517.1c is an offspring of "sighted" C3H female (i.e. the congenic C3H stock carrying the BALB/c version of the Pde6b gene) mated to C57BL/6J male that received ENU. Congenic on C3H/HeH |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Orphanet associated rare diseases, based on orthologous gene matching
