C57BL/6J-Tg(Igfn1-eGFP)3H/H
| Status | Available to order |
| EMMA ID | EM:16010 |
| Citation information | RRID:IMSR_EM:16010 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Tg(Igfn1-eGFP)3H/H |
| Alternative name | C57BL/6J-Tg(Igfn1-eGFP)3H/H |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Igfn1-eGFP)3H |
| Gene/Transgene symbol | Tg(Igfn1-eGFP)3H |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This IGFN1(D1-D3) transgenic strain was designed to over-express a fragment of a large protein of unknown function (IGFN1), which exists in many different variants. IGFN1 was identified as an interacting partner to the KY protein, which is associated with a muscular dystrophy. The transgene contains only the first three domains of this protein fused to the fluorescent reporter GFP. It is expressed only in skeletal muscle. The purpose of this line was to test the effect of the overexpression and, on the other hand, cross it to the neuromuscular mutant ky and study possible genetic interactions. |
| Breeding history | Coisogenic on C57BL/6J |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |