- preweaning lethality, complete penetrance / IMPC
- abnormal liver morphology / IMPC
- abnormal kidney morphology / IMPC
- abnormal caudal vertebrae morphology / IMPC
- abnormal placenta morphology / IMPC
- small liver / IMPC
- decreased locomotor activity / IMPC
- prenatal lethality prior to heart atrial septation / IMPC
- abnormal spleen morphology / IMPC
- enlarged spleen / IMPC
- increased freezing behavior / IMPC
- small kidney / IMPC
B6.C(C3H)-Cacna1cm1H/H
| Status | Available to order |
| EMMA ID | EM:16040 |
| Citation information | RRID:IMSR_EM:16040 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.C(C3H)-Cacna1cm1H/H |
| Alternative name | C57BL/6J.Cg-Cacna1c |
| Strain type | Induced Mutant Strains |
| Allele/Transgene symbol | Cacna1cG145D |
| Gene/Transgene symbol | Cacna1c |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This strain carries a G to A change at base 87801735 on sequence ref NT_039353.8. This results in an aspartic acid replacing a glycine at amino acid 1540 (ENSMUSP00000108413). |
| Phenotypic information | Homozygous:No phenotype data availableHeterozygous:No phenotype data available |
| Breeding history | Original mutant (EMRC/330.4i male) - an offspring of a BALB/cAnN ENU treated male mated to a C3H/HeH female. Now congenic on C57BL/6 |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (gene matching)
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