B6.C(C3H)-Cacna1cm1H/H

Status

Available to order

EMMA IDEM:16040
Citation informationRRID:IMSR_EM:16040 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameB6.C(C3H)-Cacna1cm1H/H
Alternative nameC57BL/6J.Cg-Cacna1c/H
Strain typeInduced Mutant Strains
Allele/Transgene symbolCacna1cG145D
Gene/Transgene symbolCacna1c

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis strain carries a G to A change at base 87801735 on sequence ref NT_039353.8. This results in an aspartic acid replacing a glycine at amino acid 1540 (ENSMUSP00000108413).
Phenotypic informationHomozygous:
No phenotype data available

Heterozygous:
No phenotype data available
Breeding historyOriginal mutant (EMRC/330.4i male) - an offspring of a BALB/cAnN ENU treated male mated to a C3H/HeH female. Now congenic on C57BL/6
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC
  • abnormal liver morphology / IMPC
  • abnormal kidney morphology / IMPC
  • abnormal caudal vertebrae morphology / IMPC
  • abnormal placenta morphology / IMPC
  • small liver / IMPC
  • decreased locomotor activity / IMPC
  • prenatal lethality prior to heart atrial septation / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • increased freezing behavior / IMPC
  • small kidney / IMPC

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Availabilities

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Practical information

Genotyping protocol

Example health report
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