C57BL/6NTac-Zfhx3em1H/H

Status

Available to order

EMMA IDEM:16045
Citation informationRRID:IMSR_EM:16045 

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International strain nameC57BL/6NTac-Zfhx3em1H/H
Alternative nameC57BL/6NTac-Zfhx3/H
Strain typeEndonuclease-mediated
Allele/Transgene symbolZfhx3em1H
Gene/Transgene symbolZfhx3

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse strain carries a conditional Zfhx3 allele generated by CRISPR/Cas9 gene editing of exon ENSMUSE00000326565. The CRISPR/Cas9 reagents were injected into 1-cell stage embryos
Phenotypic informationHomozygous:
No phenotype data available

Heterozygous:
No phenotype data available
Breeding historyCoisogenic on C57BL/6NTac
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • decreased body size / MGI
  • hypoactivity / MGI
  • abnormal eating behavior / MGI
  • premature death / MGI
  • abnormal fertility/fecundity / MGI
  • no abnormal phenotype detected / MGI
  • decreased thyroid-stimulating hormone level / MGI
  • decreased growth hormone level / MGI
  • endocrine/exocrine gland phenotype / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • abnormal circadian behavior / MGI
  • shortened circadian behavior period / MGI
  • arrhythmic circadian behavior persistence / MGI
  • abnormal circadian behavior phase / MGI
  • advanced circadian behavior phase / MGI
  • abnormal circardian behavior entrainment / MGI

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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Practical information

Genotyping protocol

Example health report
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