IMPC phenotypes (gene matching)
C57BL/6N-Mir124a-2tm1Wtsi/Ics
| Status | Available to order |
| EMMA ID | EM:16068 |
| Citation information | RRID:IMSR_EM:16068 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Mir124a-2tm1Wtsi/Ics |
| Alternative name | Mir124a-2tm1(mirKO)Wtsi/Ics |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Mir124a-2tm1Wtsi |
| Gene/Transgene symbol | Mir124a-2 |
Information from provider
| Provider | ICS, Institut Clinique de la Souris |
| Provider affiliation | ICS, Institut Clinique de la Souris |
| Genetic information | The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion of size 164 starting at position 17849824 and ending at position 17849988 of Chromosome 3 (Build GRCm39). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and finally an FRT site. |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | Pure C57BL/6N genetic background. Current background: C57BL/6N 0.0854%, C57BL/6NCrl 50%, C57BL/6NTac 49.9146% |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Literature references
- Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.;Meziane Hamid, Birling Marie-Christine, Wendling Olivia, Leblanc Sophie, Dubos Aline, Selloum Mohammed, Pavlovic Guillaume, Sorg Tania, Kalscheuer Vera M, Billuart Pierre, Laumonnier Frédéric, Chelly Jamel, van Bokhoven Hans, Herault Yann, ;2022;Biomedicines;10;; 36551904