B6N(Cg)-Agbl2^tm1.1Ics/Ics

Status	Available to order
EMMA ID	EM:16125
Citation information	RRID:IMSR_EM:16125 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6N(Cg)-Agbl2^tm1.1Ics/Ics
Alternative name	Agbl2tm1.1Ics/Ics
Strain type	Targeted Mutant Strains : Conditional mutation
Allele/Transgene symbol	Agbl2^tm1.1Ics
Gene/Transgene symbol	Agbl2

Information from provider

Provider	Annie Andrieux
Provider affiliation	Physiopathologies of the Cytoskeleton, Grenoble Institut Neuroscience
Genetic information	A loxP site was inserted into intron 8 and an FRT site flanked neomycin resistance gene cassette followed by a second loxP site were inserted into intron 9. The neo cassette was removed through subsequent flp-mediated recombination (MGI:2158498), leaving a conditional-ready allele with exon 9 (ENSMUSE00001231910; GRCm39, Agbl2-201) floxed.
Phenotypic information	Homozygous: N/A Heterozygous: N/A
Breeding history	86.7% C57BL/6N. The line was backcrossed 3 times with C57BL/6N mice (C57BL/6NTac 86.7188, C57BL/6J 0.7812, 129/SvPas 12.5).
References	The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.;Tort Olivia, Tanco Sebastián, Rocha Cecilia, Bièche Ivan, Seixas Cecilia, Bosc Christophe, Andrieux Annie, Moutin Marie-Jo, Avilés Francesc Xavier, Lorenzo Julia, Janke Carsten, ;2014;Molecular biology of the cell;25;3017-27; 25103237
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)

increased grip strength / IMPC

Literature references

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.;Tort Olivia, Tanco Sebastián, Rocha Cecilia, Bièche Ivan, Seixas Cecilia, Bosc Christophe, Andrieux Annie, Moutin Marie-Jo, Avilés Francesc Xavier, Lorenzo Julia, Janke Carsten, ;2014;Molecular biology of the cell;25;3017-27; 25103237

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.
Not found what you were looking for? Search here for other strains available from EMMA.

INFRAFRONTIER^® and European Mouse Mutant Archive - EMMA^® are registered trademarks at the European Union Intellectual Property Office (EUIPO).

B6N(Cg)-Agbl2tm1.1Ics/Ics