C57BL/6N-Rab38tm1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:16153 |
| Citation information | RRID:IMSR_EM:16153 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Rab38tm1Ics/Ics |
| Alternative name | Rab38tm1Ics/Ics |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Rab38tm1Ics |
| Gene/Transgene symbol | Rab38 |
Information from provider
| Provider | Catherine Leon |
| Provider affiliation | INSERM UMR_S1255 / EFS-Alsace |
| Genetic information | A loxP site was inserted into intron 1 and an FRT site-flanked neomycin resistance gene cassette followed by a second loxP site were inserted into intron 2. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exon 2 (ENSMUSE00000200397; GRCm39, Rab38-201) floxed. |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | 100% C57BL/6N (C57BL/6N 1.07%, C57BL/6NCrl 50%, C57BL/6NTac 48.92%). |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Literature references
- Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis.;Aguilar Alicia, Weber Josiane, Boscher Julie, Freund Monique, Ziessel Catherine, Eckly Anita, Magnenat Stéphanie, Bourdon Catherine, Hechler Béatrice, Mangin Pierre H, Gachet Christian, Lanza François, Léon Catherine, ;2019;Blood advances;3;2368-2380; 31399401