- abnormal cerebral cortex morphology / MGI
- hypoactivity / MGI
- no phenotypic analysis / MGI
- abnormal response to novel object / MGI
- nervous system phenotype / MGI
- abnormal nervous system physiology / MGI
- cellular phenotype / MGI
- vision/eye phenotype / MGI
- abnormal lens development / MGI
- decreased susceptibility to neuronal excitotoxicity / MGI
- increased striatum area / MGI
B6;129-Casp6tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:16179 |
| Citation information | RRID:IMSR_EM:16179 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Casp6tm1.1Ics/Ics |
| Alternative name | Casp6tm1.1Ics/Ics |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Casp6tm1.1Ics |
| Gene/Transgene symbol | Casp6 |
Information from provider
| Provider | Jerome Estaquier |
| Provider affiliation | Centre de recherche du CHUQ (CHUL) |
| Genetic information | A loxP site was inserted into intron1 and a second loxP site and an FRT site-flanked neomycin resistance gene cassette were inserted into intron 3. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with floxed exons 2 (ENSMUSE00001243097) and 3 (ENSMUSE00001269048) (GRCm39, Casp6-201). |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | 129/SvPas 12.5%, C57BL/6NTac 85.94%, C57BL/6J 1.56% |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
MGI phenotypes (gene matching)
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