C57BL/6N-Prrx1tm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:16196 |
| Citation information | RRID:IMSR_EM:16196 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Prrx1tm1.1Ics/Ics |
| Alternative name | Prrx1tm1.1Ics/Ics |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Prrx1tm1.1Ics |
| Gene/Transgene symbol | Prrx1 |
Information from provider
| Provider | Arnaud MAILLEUX |
| Provider affiliation | Université Paris Cité - ERL CNRS 8252), Faculté de Médecine Paris Diderot Paris 7 - site Bichat, Centre de Recherche sur l |
| Genetic information | A loxP site was inserted into intron 1 and a second loxP site and an FRT site-flanked neomycin resistance gene cassette site were inserted into intron 2. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with floxed exon 2 (GRCm38, Prrx1-201 ENSMUSE00001331660). |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | C57BL/6NCrl 99.61%, C57BL/6NTac 0.39% |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Literature references
- Uncovering an antifibrotic Prrx1-lineage mesenchymal cell subpopulation in fibrotic lungs.;Homps-Legrand Meline, Jaillet Madeleine, Deneuville Lou, Gautier Gregory, Crestani Bruno, Mailleux Arnaud A, ;2025;Disease models & mechanisms;18;; 40856011