C57BL/6N-Gnaltm1.1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:16213 |
| Citation information | RRID:IMSR_EM:16213 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Gnaltm1.1Ics/Ics |
| Alternative name | Gnaltm1.1Ics/Ics |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Gnaltm1.1Ics |
| Gene/Transgene symbol | Gnal |
Information from provider
| Provider | Jean-Antoine Girault |
| Provider affiliation | Institut du Fer à Moulin, U1270, Inserm |
| Genetic information | A loxP site was inserted into intron 2 and an FRT site-flanked neomycin resistance gene cassette was inserted into intron 4. Subsequent flp-mediated recombination, leaded to a conditional-ready allele with floxed exon 3 (ENSMUSE00000453976) and exon 4 (ENSMUSE00000453971; GRCm39, Gnal-201). |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | 100% C57BL/6N (C57BL/6NCrl 99,90% C57BL/6NTac 0,10%) |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Literature references
- Characterization of mice with cell type-specific Gnal loss of function provides insights on GNAL-linked dystonia.;Longueville Sophie, Yuan Ruiyi, Naon Claire, Valjent Emmanuel, Pelosi Assunta, Roze Emmanuel, Mariani Louise-Laure, Girault Jean-Antoine, Hervé Denis, ;2025;Neurobiology of disease;215;107071; 40902679