C57BL/6NCrl-Htttm5.1Ics/Ics

Status

Available to order

EMMA IDEM:16215
Citation informationRRID:IMSR_EM:16215 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameC57BL/6NCrl-Htttm5.1Ics/Ics
Alternative nameHtttm3.1Ics/Ics
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolHtttm5.1Ics
Gene/Transgene symbolHtt

Information from provider

ProviderFrédéric Saudou
Provider affiliationGrenoble Institut des Neurosciences (GIN)
Genetic informationThe aspartic acid 564 (GAT) in exon 13 (ENSMUSE00001232286) was replaced by a glutamic acid, an asparagine, a leucine, a tyrosine, a phenylalanine, a glutamine and a serine coding sequence (GAA AAC CTG TAC TTC CAG TCC; c.1691_1692delATins AAAACCTGTACTTCCAGTCC p.D564ENLYFQS). A floxed neoR-protamine cre selection cassette was inserted and auto-excised upstream exon 13 leaving a single loxP site.
Phenotypic informationHomozygous:
N/A

Heterozygous:
N/A
Breeding history100% C57BL/6NCrl
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

IMPC phenotypes (gene matching)
  • increased grip strength / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • embryonic lethality prior to organogenesis / IMPC

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
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