C57BL/6N-Lrbatm1.1Ics/Ics

Status

Available to order

EMMA IDEM:16217
Citation informationRRID:IMSR_EM:16217 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6N-Lrbatm1.1Ics/Ics
Alternative nameLrbatm1.1Ics/Ics
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolLrbatm1.1Ics
Gene/Transgene symbolLrba

Information from provider

ProviderFrédéric Rieux-laucat
Provider affiliationInstitut Imagine
Genetic informationA loxP site was inserted into intron 1 and an FRT site-flanked neomycin resistance gene cassette was inserted into intron 2. Subsequent flp-mediated recombination led to a conditional-ready allele with floxed exon 2 (ENSMUSE00000331229; GRCm39, Lrba-201).
Phenotypic informationHomozygous:
N/A

Heterozygous:
N/A
Breeding history100% C57BL/6N (C57BL/6NCrl 99,90% C57BL/6NTac 0,10%)
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal ear position / IMPC
  • increased circulating amylase level / IMPC
  • increased circulating calcium level / IMPC
  • absent pinna reflex / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased circulating HDL cholesterol level / IMPC
  • decreased circulating chloride level / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased circulating total protein level / IMPC
  • increased circulating cholesterol level / IMPC
  • increased circulating creatinine level / IMPC
MGI phenotypes (gene matching)
  • increased length of allograft survival / MGI
  • increased regulatory T cell number / MGI
  • impaired natural killer cell mediated cytotoxicity / MGI
  • decreased susceptibility to graft versus host disease / MGI
  • abnormal NK cell physiology / MGI
  • increased myeloid cell number / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).