IMPC phenotypes (gene matching)
C57BL/6J-Magel2em1.1H/H
| Status | Available to order |
| EMMA ID | EM:16969 |
| Citation information | RRID:IMSR_EM:16969 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Magel2em1.1H/H |
| Alternative name | C57BL/6J-Magel |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Magelem1.1H |
| Gene/Transgene symbol | Magel2 |
Information from provider
| Provider | Theresa Strong |
| Provider affiliation | |
| Genetic information | This strain was generated by Cre mediated excision of floxed Magel2 exon ENSMUSE00000497291 in the strain C57BL/6J-Magel2em1H/H (EM: 16968). This gene is imprinted, when deleted it should be maintained through the female line for breeding and through the male line when producing experimental animals. |
| Phenotypic information | Homozygous:not determinedHeterozygous:67% birth survival; reduced birth weight (90% of WT); delayed growth; reduced tibia length; reduced fat/lean ratio; deficits in activity and sleep-like patterns when paternally inherited |
| Breeding history | Coisogenic on C57BL/6J |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |