MGI phenotypes (allele matching)
B6;129P2-Sycntm1Rja/H
| Status | Available to order |
| EMMA ID | EM:01720 |
| Citation information | RRID:IMSR_EM:01720 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Sycntm1Rja/H |
| Alternative name | B6,129-Sycn |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Sycntm1Rja |
| Gene/Transgene symbol | Sycn |
Information from provider
| Provider | Dr. A. J. Morton |
| Provider affiliation | Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD |
| Genetic information | Exon 1, encoding residues 1-132, was replaced by a pBluescript/neomycin selection cassette by homologous recombination. |
| Phenotypic information | Normal growth and fertility. Pancreatic secretion compromised. Pancreatic hypertrophy and elevated amylase levels. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion.;Antonin Wolfram, Wagner Martin, Riedel Dietmar, Brose Nils, Jahn Reinhard, ;2002;Molecular and cellular biology;22;1545-54; 11839820