MGI phenotypes (allele matching)
- lethality, complete penetrance / MGI
C.NOD-Tg(Ins2-crmA)27Ngkh/Orl
| Status | Available to order |
| EMMA ID | EM:01726 |
| Citation information | RRID:IMSR_EM:01726 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C.NOD-Tg(Ins2-crmA)27Ngkh/Orl |
| Alternative name | RIP-CrmA 27 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Ins2-crmA)27Ngkh |
| Gene/Transgene symbol | Tg(Ins2-crmA)27Ngkh |
Information from provider
| Provider | Nicolas Glaichenhaus |
| Provider affiliation | INSERM U561 - Hopital Saint Vincent de Paul, Paris |
| Genetic information | The viral cytokine response modifier A (CrmA) cDNA was cloned under the control of the rat rat insulin II promoter (RIP). |
| Phenotypic information | No defects. |
| Breeding history | The original strain was bred for 7 generations on the BALB/c genetic background. Maintained in an heterozygous state since homozygous mice are not viable. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- lethality, complete penetrance / MGI
Literature references
- Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells.;Hugues Stéphanie, Mougneau Evelyne, Ferlin Walter, Jeske Dirk, Hofman Paul, Homann Dirk, Beaudoin Lucie, Schrike Corinne, Von Herrath Matthias, Lehuen Agnès, Glaichenhaus Nicolas, ;2002;Immunity;16;169-81; 11869679