| Status | Available to order |
| EMMA ID | EM:01736 |
| Citation information | RRID:IMSR_EM:01736 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Ptprctm1Holm/H |
| Alternative name | Ptprc |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Ptprctm1Holm |
| Gene/Transgene symbol | Ptprc |
| Provider | Denis Alexander |
| Provider affiliation | The Babraham Institute, Babraham, Cambridge, CB2 4PB |
| Genetic information | A neomycin resistance cassette (corrected for a point mutation believed to affect the transformation efficiency of ES cells) was used to disrupt exon 9, resulting in the introduction of several stop codons downstream of the insertion. |
| Phenotypic information | Defective lymphocyte development, more severe in T lineage. Severe combined immunodeficiency. |
| References |
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| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Orphanet associated rare diseases, based on orthologous gene matching
