FVB-Tg(CEPHY285E6)67Hgc/Orl
| Status | Available to order |
| EMMA ID | EM:01748 |
| Citation information | RRID:IMSR_EM:01748 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Tg(CEPHY285E6)67Hgc/Orl |
| Alternative name | YAC Lg 67 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CEPHY285E6)67Hgc |
| Gene/Transgene symbol | Tg(CEPHY285E6)67Hgc |
Information from provider
| Provider | Edward Rubin |
| Provider affiliation | Laurence Berkeley National Laboratory, Human Genome Center - 1, cyclotron Road, Berkeley, CA 94720, |
| Genetic information | Transgenic for a YAC carrying a fragment of human chromosome 21, containing the KCNJ6 (potassium channel, subfamily J, member 6; also called GIRK2 or KIR3.2) gene. |
| Phenotypic information | Trisomy 21. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Literature references
- Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.;Smith D J, Zhu Y, Zhang J, Cheng J F, Rubin E M, ;1995;Genomics;27;425-34; 7558023
- Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice.;Cooper Ayelet, Grigoryan Gayane, Guy-David Liora, Tsoory Michael M, Chen Alon, Reuveny Eitan, ;2012;Proceedings of the National Academy of Sciences of the United States of America;109;2642-7; 22308328