B6;129-Tg(UBC-Dclre1c,-GFP)6Jpdv/Orl

Status	Available to order
EMMA ID	EM:01806
Citation information	RRID:IMSR_EM:01806 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6;129-Tg(UBC-Dclre1c,-GFP)6Jpdv/Orl
Alternative name	ArtT
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(UBC-Dclre1c,-GFP)6Jpdv
Gene/Transgene symbol	Tg(UBC-Dclre1c,-GFP)6Jpdv

Information from provider

Provider	Jean-Pierre De Villartay
Provider affiliation	CRBS (Centre de Recherche en Biomédecine), Inserm UMR 1109 (Immuno-Rhumatologie Moléculaire, IRM)
Genetic information	The transgene contains a floxed murine Artemis (DNA cross-link repair 1C, Dclre1c) coding sequence fused to a tandem affinity purification (TAP) tag sequence.
Phenotypic information	Not known.
Breeding history	Backcrossed to C57BL/6, F2.
References	A generic protein purification method for protein complex characterization and proteome exploration.;Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, Séraphin B, ;1999;Nature biotechnology;17;1030-2; 10504710 Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.;Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F, Tezcan I, Sanal O, Bertrand Y, Philippe N, Fischer A, de Villartay J P, ;2001;Cell;105;177-86; 11336668 Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.;Soulas-Sprauel Pauline, Le Guyader Gwenaël, Rivera-Munoz Paola, Abramowski Vincent, Olivier-Martin Christelle, Goujet-Zalc Cécile, Charneau Pierre, de Villartay Jean-Pierre, ;2007;The Journal of experimental medicine;204;1717-27; 17606631

Information from EMMA

Archiving centre	CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France

Literature references

A generic protein purification method for protein complex characterization and proteome exploration.;Rigaut G, Shevchenko A, Rutz B, Wilm M, Mann M, Séraphin B, ;1999;Nature biotechnology;17;1030-2; 10504710
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.;Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F, Tezcan I, Sanal O, Bertrand Y, Philippe N, Fischer A, de Villartay J P, ;2001;Cell;105;177-86; 11336668
Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.;Soulas-Sprauel Pauline, Le Guyader Gwenaël, Rivera-Munoz Paola, Abramowski Vincent, Olivier-Martin Christelle, Goujet-Zalc Cécile, Charneau Pierre, de Villartay Jean-Pierre, ;2007;The Journal of experimental medicine;204;1717-27; 17606631

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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