FVB-Tg(Nefh/EGFP)1Eyer/Orl
| Status | Available to order |
| EMMA ID | EM:01839 |
| Citation information | RRID:IMSR_EM:01839 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Tg(Nefh/EGFP)1Eyer/Orl |
| Alternative name | NFH-GFP |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Nefh/EGFP)1Eyer |
| Gene/Transgene symbol | Tg(Nefh/EGFP)1Eyer |
Information from provider
| Provider | Joel Eyer |
| Provider affiliation | INSERM, University of Angers |
| Genetic information | Transgenic mice expressing a fusion gene between the full sequence of mouse neurofilament high subunit (Nefh or Nfh) and the green-fluorescent protein (GFP) reporter sequence. This fluorescent marker is expressed only in neurons, where it is co-assembled with the endogenous neurofilament cytoskeleton, and transported in axons, up to synapses. Therefore, this new fluorescent marker is expressed only in neurons and the expression follows the endogenous neurofilament expression. |
| Phenotypic information | These mice do not show an abnormal "in-cage" phenotype. |
| Breeding history | Backcrossed up to the 6th generation. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous FVB males |
Literature references
- Neurofilament high molecular weight-green fluorescent protein fusion is normally expressed in neurons and transported in axons: a neuronal marker to investigate the biology of neurofilaments.;Letournel F, Bocquet A, Perrot R, Dechaume A, Guinut F, Eyer J, Barthelaix A, ;2006;Neuroscience;137;103-11; 16289584