C3HeB/FeJ-Chold8/Ieg

Status

Available to order

EMMA IDEM:01862
Citation informationRRID:IMSR_EM:01862 

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International strain nameC3HeB/FeJ-Chold8/Ieg
Alternative nameCHO019
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolChold8
Gene/Transgene symbolChold8

Information from provider

ProviderEckhard Wolf
Provider affiliationInstitute of Molecular Animal Breeding and Biotechnologies
Genetic informationLow total cholesterol concentration in plasma.
Phenotypic informationMutated animals show no major defects. Phenotyping results of offspring from intercrosses of affected mice suggest that homozygous mutant mice might be viable with extremely low cholesterol values in plasma.
References
  • Genome-wide, large-scale production of mutant mice by ENU mutagenesis.;Hrabé de Angelis M H, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R, ;2000;Nature genetics;25;444-7; 10932192
  • The large-scale Munich ENU-mouse-mutagenesis screen.;Soewarto D, Fella C, Teubner A, Rathkolb B, Pargent W, Heffner S, Marschall S, Wolf E, Balling R, Hrabé de Angelis M, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;507-10; 10886013
  • Identification of immunological relevant phenotypes in ENU mutagenized mice.;Flaswinkel H, Alessandrini F, Rathkolb B, Decker T, Kremmer E, Servatius A, Jakob T, Soewarto D, Marschall S, Fella C, Behrendt H, Ring J, Wolf E, Balling R, Hrabé de Angelis M, Pfeffer K, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;526-7; 10886016
  • Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.;Rathkolb B, Fuchs E, Kolb H J, Renner-Müller I, Krebs O, Balling R, Hrabé de Angelis M, Wolf E, ;2000;Experimental physiology;85;635-44; 11187959
  • Generation of ENU-induced mouse mutants with hypocholesterolemia: novel tools for dissecting plasma lipoprotein homeostasis.;Aigner Bernhard, Rathkolb Birgit, Mohr Manuela, Klempt Martina, Hrabé de Angelis Martin, Wolf Eckhard, ;2007;Lipids;42;731-7; 17554576

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Literature references

  • Genome-wide, large-scale production of mutant mice by ENU mutagenesis.;Hrabé de Angelis M H, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R, ;2000;Nature genetics;25;444-7; 10932192
  • The large-scale Munich ENU-mouse-mutagenesis screen.;Soewarto D, Fella C, Teubner A, Rathkolb B, Pargent W, Heffner S, Marschall S, Wolf E, Balling R, Hrabé de Angelis M, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;507-10; 10886013
  • Identification of immunological relevant phenotypes in ENU mutagenized mice.;Flaswinkel H, Alessandrini F, Rathkolb B, Decker T, Kremmer E, Servatius A, Jakob T, Soewarto D, Marschall S, Fella C, Behrendt H, Ring J, Wolf E, Balling R, Hrabé de Angelis M, Pfeffer K, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;526-7; 10886016
  • Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.;Rathkolb B, Fuchs E, Kolb H J, Renner-Müller I, Krebs O, Balling R, Hrabé de Angelis M, Wolf E, ;2000;Experimental physiology;85;635-44; 11187959
  • Generation of ENU-induced mouse mutants with hypocholesterolemia: novel tools for dissecting plasma lipoprotein homeostasis.;Aigner Bernhard, Rathkolb Birgit, Mohr Manuela, Klempt Martina, Hrabé de Angelis Martin, Wolf Eckhard, ;2007;Lipids;42;731-7; 17554576

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

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