C3HeB/FeJ-Chold8/Ieg
Status | Available to order |
EMMA ID | EM:01862 |
Citation information | RRID:IMSR_EM:01862 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C3HeB/FeJ-Chold8/Ieg |
Alternative name | CHO019 |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | Chold8 |
Gene/Transgene symbol | Chold8 |
Information from provider
Provider | Eckhard Wolf |
Provider affiliation | Institute of Molecular Animal Breeding and Biotechnologies |
Genetic information | Low total cholesterol concentration in plasma. |
Phenotypic information | Mutated animals show no major defects. Phenotyping results of offspring from intercrosses of affected mice suggest that homozygous mutant mice might be viable with extremely low cholesterol values in plasma. |
References |
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Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Literature references
- Genome-wide, large-scale production of mutant mice by ENU mutagenesis.;Hrabé de Angelis M H, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R, ;2000;Nature genetics;25;444-7; 10932192
- The large-scale Munich ENU-mouse-mutagenesis screen.;Soewarto D, Fella C, Teubner A, Rathkolb B, Pargent W, Heffner S, Marschall S, Wolf E, Balling R, Hrabé de Angelis M, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;507-10; 10886013
- Identification of immunological relevant phenotypes in ENU mutagenized mice.;Flaswinkel H, Alessandrini F, Rathkolb B, Decker T, Kremmer E, Servatius A, Jakob T, Soewarto D, Marschall S, Fella C, Behrendt H, Ring J, Wolf E, Balling R, Hrabé de Angelis M, Pfeffer K, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;526-7; 10886016
- Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.;Rathkolb B, Fuchs E, Kolb H J, Renner-Müller I, Krebs O, Balling R, Hrabé de Angelis M, Wolf E, ;2000;Experimental physiology;85;635-44; 11187959
- Generation of ENU-induced mouse mutants with hypocholesterolemia: novel tools for dissecting plasma lipoprotein homeostasis.;Aigner Bernhard, Rathkolb Birgit, Mohr Manuela, Klempt Martina, Hrabé de Angelis Martin, Wolf Eckhard, ;2007;Lipids;42;731-7; 17554576
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