C57BL/6J-Tg(Vpreb1-IL2RB)F133Ilm/H
| Status | Available to order |
| EMMA ID | EM:01895 |
| Citation information | RRID:IMSR_EM:01895 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6J-Tg(Vpreb1-IL2RB)F133Ilm/H |
| Alternative name | Tg(-214VpreB1-huCD122)F133Lmb |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Vpreb1-IL2RB)F133Ilm |
| Gene/Transgene symbol | Tg(Vpreb1-IL2RB)F133Ilm |
Information from provider
| Provider | Dr Lill Martensson |
| Provider affiliation | The Babraham Institute, Babraham, Cambridge, CB2 4PB |
| Genetic information | The human interleukin 2 receptor, beta (IL2RB or CD122) is expressed on the cell surface of precursor B-lymphocytes (stage specific) and as mRNA in some other tissues. |
| Phenotypic information | The Vpreb1 promoter/enhancer-driven reporter gene (human IL2RB or CD122) gives rise to B-lymphocyte stage-specific expression. However, it is also expressed in other tissues. Expression is copy number-dependent. |
| References |
|
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- The VpreB1 enhancer drives developmental stage-specific gene expression in vivo.;Licence Steve, Persson Christine, Mundt Cornelia, Mårtensson Inga-Lill, ;2003;European journal of immunology;33;1117-26; 12672078