STOCK Tg(CAG-AVEN)1Zrng/Ieg
| Status | Available to order |
| EMMA ID | EM:01917 |
| Citation information | RRID:IMSR_EM:01917 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tg(CAG-AVEN)1Zrng/Ieg |
| Alternative name | beta-actin-Aven |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CAG-AVEN)1Zrng |
| Gene/Transgene symbol | Tg(CAG-AVEN)1Zrng |
Information from provider
| Provider | Martin Zoernig |
| Provider affiliation | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, University of Frankfurt |
| Genetic information | For the ubiquitous overexpression of human AVEN its cDNA sequence was cloned into the pCAGGS vector. This vector was provided by H. Niwa, RIKEN Center for Dev. Biology, Kobe, Japan, and contains a chicken beta-actin promoter, a HCMV enhancer and a polyadenylation signal, provided by the rabbit beta-globin sequence. Mice significantly overexpress AVEN only in the heart. |
| Phenotypic information | The mice appear normal. So far, they have been kept only as heterozygotes, which breed perfectly normal. Analysis of mutant mice is still ongoing. |
| Breeding history | Backcrossed into C57BL/6 for 4 generations. |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |