MGI phenotypes (allele matching)
STOCK Mut1293/H
| Status | Available to order |
| EMMA ID | EM:01950 |
| Citation information | RRID:IMSR_EM:01950 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Mut1293/H |
| Alternative name | MUT/1293 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Mut1293 |
| Gene/Transgene symbol | Mut1293 |
Information from provider
| Provider | Bruce Cattanach |
| Provider affiliation | MRC Harwell, Didcot, Oxon, OX11 0RD |
| Genetic information | |
| Phenotypic information | Heterozygotes are small at birth and weaning. Broad head, bulging eyes, some have ear problems i.e. a build up of a hard white deposit and signs of blood. Penetrance of the phenotype and viability of affected individuals to weaning is good. Homozygotes die post implantation, or survive for longer but are oedematous and have skeletal bone/cartilage abnormalities; limited intercross data suggest that they do not survive post-natally. |
| Breeding history | Original background: (C3H/HeH x 101/H) x PT. Maintained background: C3H/HeH x 101/H. Breeding History: Backcrossed to C3H/HeH x 101/H for several generations. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191