B6;C-Hoxd13Dyc/Orl

Status

Available to order

EMMA IDEM:01958
Citation informationRRID:IMSR_EM:01958 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6;C-Hoxd13Dyc/Orl
Alternative nameBALB/cHoxd13Dyc
Strain typeSpontaneous
Allele/Transgene symbolHoxd13Dyc
Gene/Transgene symbolHoxd13

Information from provider

ProviderYann HERAULT
Provider affiliationTAAM-CDTA UPS44, CNRS-TAAM – Typing and Archiving of Animal Models
Genetic informationSpontaneous mutation.
Phenotypic informationHeterozygous have smaller digits 2 and 5; homozygous have all digits but smaller than wild-type, syndactyly of digit 4 and 5 and a sixth digit is present. They do not have preputial gland.
Breeding historyAnimals are N2F2 for BALB/c x C57BL/6J.
References
  • Fork stalling and template switching as a mechanism for polyalanine tract expansion affecting the DYC mutant of HOXD13, a new murine model of synpolydactyly.;Cocquempot Olivier, Brault Véronique, Babinet Charles, Herault Yann, ;2009;Genetics;183;23-30; 19546318

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • brachydactyly / MGI
  • abnormal carpal bone morphology / MGI
  • syndactyly / MGI
  • abnormal autopod morphology / MGI
  • male infertility / MGI
  • abnormal metatarsal bone morphology / MGI
  • abnormal metacarpal bone morphology / MGI
  • polysyndactyly / MGI
  • abnormal tarsal bone morphology / MGI
  • abnormal limb development / MGI
  • abnormal digit development / MGI
  • absent male preputial gland / MGI
  • abnormal bone ossification / MGI
  • abnormal hallux morphology / MGI
  • postaxial polydactyly / MGI
MGI phenotypes (gene matching)
  • delayed bone ossification / MGI
  • rectal prolapse / MGI
  • abnormal forelimb morphology / MGI
  • abnormal carpal bone morphology / MGI
  • absent carpal bone / MGI
  • polydactyly / MGI
  • syndactyly / MGI
  • interdigital webbing / MGI
  • abnormal autopod morphology / MGI
  • abnormal smooth muscle morphology / MGI
  • decreased body weight / MGI
  • reduced male fertility / MGI
  • male infertility / MGI
  • abnormal seminal vesicle morphology / MGI
  • abnormal embryonic tissue morphology / MGI
  • abnormal digit morphology / MGI
  • brachyphalangia / MGI
  • brachydactyly / MGI
  • abnormal metatarsal bone morphology / MGI
  • abnormal metacarpal bone morphology / MGI
  • delayed endochondral bone ossification / MGI
  • polysyndactyly / MGI
  • short radius / MGI
  • short ulna / MGI
  • bowed ulna / MGI
  • bowed radius / MGI
  • sacral vertebral fusion / MGI
  • short metacarpal bones / MGI
  • short metatarsal bones / MGI
  • decreased metacarpal bone number / MGI
  • decreased metatarsal bone number / MGI
  • abnormal anus morphology / MGI
  • abnormal tarsal bone morphology / MGI
  • ectrodactyly / MGI
  • abnormal phalanx morphology / MGI
  • limbs/digits/tail phenotype / MGI
  • endocrine/exocrine gland phenotype / MGI
  • abnormal limb development / MGI
  • abnormal digit development / MGI
  • absent male preputial gland / MGI
  • abnormal bone ossification / MGI
  • abnormal hallux morphology / MGI
  • abnormal internal anal sphincter morphology / MGI
  • postaxial polydactyly / MGI
  • absent female preputial gland / MGI

Literature references

  • Fork stalling and template switching as a mechanism for polyalanine tract expansion affecting the DYC mutant of HOXD13, a new murine model of synpolydactyly.;Cocquempot Olivier, Brault Véronique, Babinet Charles, Herault Yann, ;2009;Genetics;183;23-30; 19546318

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).