MGI phenotypes (allele matching)
B6.129S2-P2ry1tm1Gac/Orl
| Status | Available to order |
| EMMA ID | EM:00207 |
| Citation information | RRID:IMSR_EM:00207 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-P2ry1tm1Gac/Orl |
| Alternative name | KO-P2Y1 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | P2ry1tm1Gac |
| Gene/Transgene symbol | P2ry1 |
Information from provider
| Provider | C GACHET |
| Provider affiliation | INSERM, Strasbourg |
| Phenotypic information | Inactivation of the P2ry1 gene. The coding sequence was interrupted by insertion of a PGK-neo-poly(A) cassette. Defective platelet aggregation and increased resistance to thrombosis. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
Literature references
- Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice.;Léon C, Hechler B, Freund M, Eckly A, Vial C, Ohlmann P, Dierich A, LeMeur M, Cazenave J P, Gachet C, ;1999;The Journal of clinical investigation;104;1731-7; 10606627