MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
B6;129X1-Npdc1tm1Ce/Orl
| Status | Available to order |
| EMMA ID | EM:00211 |
| Citation information | RRID:IMSR_EM:00211 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129X1-Npdc1tm1Ce/Orl |
| Alternative name | NPDC-1 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Npdc1tm1Ce |
| Gene/Transgene symbol | Npdc1 |
Information from provider
| Provider | C Evrand |
| Provider affiliation | Oncological Genetics, CNRS - UMR 8125, Villejuif |
| Phenotypic information | The Npdc1 mutant mice were generated by gene targeting in 129/SvJ ES cells. The genomic sequence (Genbank AF263513) was interrupted by the pGN plasmid sequence. This plasmid includes the lacZ gene and the neoR gene without polyadenylation sites. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6 males |
Disease and phenotype information
Literature references
- NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity.;Sansal I, Dupont E, Toru D, Evrard C, Rouget P, ;2000;Oncogene;19;5000-9; 11042687