B6.129-S100A10tm1Jwo/H

Status

Available to order

EMMA IDEM:02152
Citation informationRRID:IMSR_EM:02152 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameB6.129-S100A10tm1Jwo/H
Alternative nameFloxed p11
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolS100a10tm1Jwo
Gene/Transgene symbolS100a10

Information from provider

ProviderThomas Foulkes
Provider affiliationWindeyer Institute of Medical Sciences, University College London
Genetic informationloxP sites inserted either site of exon 2 of the S100A10 gene, allowing conditional deletion using cre recombinase-expressing mice. Published in Foulkes et al. 2006.
Phenotypic informationNone
References
  • Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.;Foulkes Thomas, Nassar Mohammed A, Lane Tim, Matthews Elizabeth A, Baker Mark D, Gerke Volker, Okuse Kenji, Dickenson Anthony H, Wood John N, ;2006;The Journal of neuroscience : the official journal of the Society for Neuroscience;26;10499-507; 17035534

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • increased thigmotaxis / MGI
  • abnormal depression-related behavior / MGI
  • abnormal response/metabolism to endogenous compounds / MGI
  • abnormal serotonin level / MGI
  • impaired behavioral response to xenobiotic / MGI

Literature references

  • Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.;Foulkes Thomas, Nassar Mohammed A, Lane Tim, Matthews Elizabeth A, Baker Mark D, Gerke Volker, Okuse Kenji, Dickenson Anthony H, Wood John N, ;2006;The Journal of neuroscience : the official journal of the Society for Neuroscience;26;10499-507; 17035534

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

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