C3H;C-Jag1Ozz/H

Status

Available to order

EMMA IDEM:02210
Citation informationRRID:IMSR_EM:02210 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC3H;C-Jag1Ozz/H
Alternative nameGENA228
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolJag1Ozz
Gene/Transgene symbolJag1

Information from provider

ProviderPatrick Nolan
Provider affiliationMedical Research Council
Phenotypic informationThis mutation was identified during a dominant ENU mutagenesis screen. Mice carrying this mutation exhibit head weaving and circling behaviour.
References
  • Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.;Nolan P M, Peters J, Vizor L, Strivens M, Washbourne R, Hough T, Wells C, Glenister P, Thornton C, Martin J, Fisher E, Rogers D, Hagan J, Reavill C, Gray I, Wood J, Spurr N, Browne M, Rastan S, Hunter J, Brown S D, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;500-6; 10886012

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • abnormal organ of Corti morphology / MGI
  • abnormal vascular development / MGI
  • enlarged pericardium / MGI
  • distended pericardium / MGI
  • corneal opacity / MGI
  • irregularly shaped pupil / MGI
  • head bobbing / MGI
  • impaired balance / MGI
  • abnormal blood vessel morphology / MGI
  • pale yolk sac / MGI
  • hemorrhage / MGI
  • intracranial hemorrhage / MGI
  • abnormal eye morphology / MGI
  • abnormal neural tube morphology / MGI
  • no abnormal phenotype detected / MGI
  • abnormal semicircular canal morphology / MGI
  • abnormal cochlear hair cell morphology / MGI
  • head shaking / MGI
  • abnormal posterior semicircular canal morphology / MGI
  • no phenotypic analysis / MGI
  • abnormal superior semicircular canal morphology / MGI
  • abnormal vitelline vasculature morphology / MGI
  • abnormal cochlear sensory epithelium morphology / MGI
  • kinked neural tube / MGI
  • embryonic growth retardation / MGI
  • abnormal vitelline vascular remodeling / MGI
  • abnormal crista ampullaris morphology / MGI
  • increased cochlear inner hair cell number / MGI
  • decreased cochlear outer hair cell number / MGI
  • decreased neuronal precursor cell number / MGI
  • head tossing / MGI
  • positive geotaxis / MGI
  • hearing/vestibular/ear phenotype / MGI
  • embryonic lethality during organogenesis / MGI
  • abnormal placement of pupils / MGI
  • abnormal semicircular canal ampulla morphology / MGI
  • increased neuron number / MGI
  • abnormal neuron differentiation / MGI
  • iris coloboma / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • embryo tissue necrosis / MGI

Literature references

  • Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.;Nolan P M, Peters J, Vizor L, Strivens M, Washbourne R, Hough T, Wells C, Glenister P, Thornton C, Martin J, Fisher E, Rogers D, Hagan J, Reavill C, Gray I, Wood J, Spurr N, Browne M, Rastan S, Hunter J, Brown S D, ;2000;Mammalian genome : official journal of the International Mammalian Genome Society;11;500-6; 10886012

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

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