STOCK andra/H
| Status | Available to order |
| EMMA ID | EM:02255 |
| Citation information | RRID:IMSR_EM:02255 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK andra/H |
| Alternative name | Andromeda |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | andra |
| Gene/Transgene symbol | andra |
Information from provider
| Provider | Richard Cornall |
| Provider affiliation | Oxford University |
| Genetic information | Unidentified single nucleotide substitution - location unknown. |
| Phenotypic information | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Breeding at archiving centre | Males were archived by sperm freezing at the time of arrival. No breeding was performed at the archiving centre. |
Literature references
- The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity.;Hoyne Gerard F, Goodnow Christopher C, ;2006;Immunological reviews;210;27-39; 16623762
- ENU-mutagenesis: insight into immune function and pathology.;Cook Matthew C, Vinuesa Carola G, Goodnow Christopher C, ;2006;Current opinion in immunology;18;627-33; 16889948