C3HeB/FeJ-yahsmts/Orl
| Status | Available to order |
| EMMA ID | EM:02396 |
| Citation information | RRID:IMSR_EM:02396 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-yahsmts/Orl |
| Alternative name | ST1 (Small Testis 1) |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | yahsmts |
| Gene/Transgene symbol | yahsmts |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, CNRS-TAAM – Typing and Archiving of Animal Models |
| Genetic information | DNA lesions after ENU treatment corresponding to: A-T (85%), G-C (14%) and small deletions (1%). |
| Phenotypic information | Homozygous males are infertile with small testes and spermatogenesis failure. Heterozygous male are fertile. |
| Breeding history | Homozygous ST1 mutants were obtained initially by mating an F0 ENU treated male to wild-type females from the same genetic background (C3HeB/FeJ), leading to at most 10 F1 males. Then each F1 male was used as a founder animal for a pedigree. F1 males were mated to wild-type females to get a maximum number of six G2 females. G2 females were subsequently and sequentially backcrossed with the F1 founder to generate 24 G3 individuals that are homozygous for a number of mutations in a Mendelian ratio of 1 out of 8. |
| References | None available |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |