IMPC phenotypes (gene matching)
STOCK Smg6Tg(SMN1*delta5)1Pks/H
| Status | Available to order |
| EMMA ID | EM:02416 |
| Citation information | RRID:IMSR_EM:02416 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Smg6Tg(SMN1*delta5)1Pks/H |
| Alternative name | SMNDelta5 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Smg6Tg(SMN1*delta5)1Pks |
| Gene/Transgene symbol | Smg6 |
Information from provider
| Provider | Nicholas Parkinson |
| Provider affiliation | University of Oxford |
| Genetic information | This line overexpresses a cDNA splice isoform of human SMN that is missing exon 5, SMNDelta5. The promoter is a 750bp fragment of the human SMN1 promoter. The transgene is stably integrated as a single copy into Intron 13 of the Smg6 locus on Chromosome 11. This transgene is maintained as a heterozygote on an FVB/N background and expresses in all tissues tested. Heterozygotes have no deleterious phenotype on a wildtype background but homozygotes are embryonic lethal. |
| Phenotypic information | None |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous FVB/N males |
| Breeding at archiving centre | Males were archived by sperm freezing on arrival. No breeding was performed at the archiving centre. |
Disease and phenotype information
MGI phenotypes (allele matching)
- embryonic lethality / MGI