B6.Cg-Tg(H2-K-TcrbP14)128Mak/Orl

Status	Available to order
EMMA ID	EM:02426
Citation information	RRID:IMSR_EM:02426 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6.Cg-Tg(H2-K-TcrbP14)128Mak/Orl
Alternative name	P14
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(H2-K-TcrbP14)128Mak
Gene/Transgene symbol	Tg(H2-K-TcrbP14)128Mak

Information from provider

Provider	Hanspeter PIRCHER
Provider affiliation	Institut für Medizinische Mikrobiologie and Hygiene
Genetic information	P14 TCR alpha and beta chain cDNA cloned into pHSE3 expression vector. Ref: Pircher at al. (1989) EMBO Journal Vol 8: pp 719-727.
Phenotypic information	None.
Breeding history	Backcrossed on C57BL/6 for N=8.
References	T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.;Pircher H, Mak T W, Lang R, Ballhausen W, Rüedi E, Hengartner H, Zinkernagel R M, Bürki K, ;1989;The EMBO journal;8;719-27; 2524380 Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen.;Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel R M, ;1989;Nature;342;559-61; 2573841

Information from EMMA

Archiving centre	CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France

Literature references

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.;Pircher H, Mak T W, Lang R, Ballhausen W, Rüedi E, Hengartner H, Zinkernagel R M, Bürki K, ;1989;The EMBO journal;8;719-27; 2524380
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen.;Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel R M, ;1989;Nature;342;559-61; 2573841
HDAC1 controls CD8+ T cell homeostasis and antiviral response.;Tschismarov Roland, Firner Sonja, Gil-Cruz Cristina, Göschl Lisa, Boucheron Nicole, Steiner Günter, Matthias Patrick, Seiser Christian, Ludewig Burkhard, Ellmeier Wilfried, ;2014;PloS one;9;e110576; 25333902

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
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Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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