MGI phenotypes (allele matching)
B6.129S2-Del(2Hoxd11-Hoxd13)29Ddu/2Orl
| Status | Available to order |
| EMMA ID | EM:02455 |
| Citation information | RRID:IMSR_EM:02455 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Del(2Hoxd11-Hoxd13)29Ddu/2Orl |
| Alternative name | Del(2Hoxd11-Hoxd13)29Ddu |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Del(2Hoxd11-Hoxd13)29Ddu |
| Gene/Transgene symbol | Del(2Hoxd11-Hoxd13)29Ddu |
Information from provider
| Provider | Denis Duboule |
| Provider affiliation | Dept of Zoology and Animal Biology , University of Geneva, Science III |
| Genetic information | Insertion of a LacZ reporter gene at the Hoxd11 locus associated with the deletion of the Hoxd13 and Hoxd12 genes. |
| Phenotypic information | Limb defects in homozygotes. |
| Breeding history | N>6 on C57BL/6J and then intercross for F>10. |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
Literature references
- Synpolydactyly in mice with a targeted deficiency in the HoxD complex.;Zákány J, Duboule D, ;1996;Nature;384;69-71; 8900279