STOCK Bmp6tm1Rob/H

Status

Available to order

EMMA IDEM:02505
Citation informationRRID:IMSR_EM:02505 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameSTOCK Bmp6tm1Rob/H
Alternative nameBmp6
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolBmp6tm1Rob
Gene/Transgene symbolBmp6

Information from provider

ProviderElizabeth Robertson
Provider affiliationSir William Dunn School of Pathology, University of Oxford
Genetic informationMice carry a null mutation in Bmp6. Locus contains neo cassette.
Phenotypic informationMice show no overt phenotype but can be used for studying the genetic redundancy of signally in the Bmp growth factor family.
Breeding historyOutcrossed onto CD1 background.
References
  • Mice lacking Bmp6 function.;Solloway M J, Dudley A T, Bikoff E K, Lyons K M, Hogan B L, Robertson E J, ;1998;Developmental genetics;22;321-39; 9664685
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal salivary gland morphology / IMPC
  • increased circulating iron level / IMPC
  • abnormal pancreas morphology / IMPC
  • increased brain size / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased hemoglobin content / IMPC
  • decreased body weight / IMPC
  • decreased startle reflex / IMPC
  • kyphosis / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased heart rate / IMPC
  • increased mean corpuscular volume / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • abnormal spine curvature / IMPC
  • decreased locomotor activity / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • abnormal brain morphology / IMPC
  • abnormal skin morphology / IMPC
MGI phenotypes (allele matching)
  • abnormal sternum ossification / MGI
  • abnormal sternum manubrium morphology / MGI
MGI phenotypes (gene matching)
  • decreased body length / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • abnormal sternum ossification / MGI
  • abnormal sternum manubrium morphology / MGI

Literature references

  • Mice lacking Bmp6 function.;Solloway M J, Dudley A T, Bikoff E K, Lyons K M, Hogan B L, Robertson E J, ;1998;Developmental genetics;22;321-39; 9664685

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
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