MGI phenotypes (gene matching)
STOCK Smad9tm1Rob/H
| Status | Available to order |
| EMMA ID | EM:02507 |
| Citation information | RRID:IMSR_EM:02507 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Smad9tm1Rob/H |
| Alternative name | Smad8 LacZ |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Smad9tm1Rob |
| Gene/Transgene symbol | Smad9 |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Genetic information | Reporter allele of Smad8 via inframe knock-in of a LacZ coding sequence into the Smad 8 locus. Expression of beta-galactosidase reflects the transcriptional activity of the endogenous Smad8 locus. Tissue sites of robust LacZ expression include the bones of the skeleton, gut endoderm and selected neural tissues. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed onto CD1. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.;Arnold Sebastian J, Maretto Silvia, Islam Ayesha, Bikoff Elizabeth K, Robertson Elizabeth J, ;2006;Developmental biology;296;104-18; 16765933