STOCK Lrig3tm1Rob/RobH

Status

Available to order

EMMA IDEM:02514
Citation informationRRID:IMSR_EM:02514 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameSTOCK Lrig3tm1Rob/RobH
Alternative nameLrig3 (Kol3)
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolLrig3tm1Rob
Gene/Transgene symbolLrig3

Information from provider

ProviderElizabeth Robertson
Provider affiliationSir William Dunn School of Pathology, University of Oxford
Genetic informationThe Lrig mouse line was generated by gene targeting and designed to create a Lrig3 null allele by preventing expression of any transcript for this gene.
Phenotypic informationUnknown - this strain is currently undergoing investigation.
Breeding historyBackcrossed to C57BL/6J
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal spleen morphology / IMPC
  • increased circulating creatine kinase level / IMPC
  • enlarged heart / IMPC
  • abnormal gait / IMPC
  • male infertility / IMPC
  • enlarged thymus / IMPC
  • abnormal skin morphology / IMPC
  • increased circulating lactate dehydrogenase level / IMPC
  • increased kidney weight / IMPC
  • increased circulating alanine transaminase level / IMPC
  • abnormal heart morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal cranium morphology / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal skeletal muscle morphology / IMPC
  • female infertility / IMPC
  • abnormal vertebral arch morphology / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • abnormal vertebrae morphology / IMPC
MGI phenotypes (gene matching)
  • abnormal lateral semicircular canal morphology / MGI
  • decreased circulating HDL cholesterol level / MGI
  • abnormal craniofacial morphology / MGI
  • short snout / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • circling / MGI
  • increased heart rate / MGI
  • decreased circulating insulin level / MGI
  • increased systemic arterial blood pressure / MGI
  • no phenotypic analysis / MGI
  • decreased lateral semicircular canal size / MGI
  • decreased posterior semicircular canal size / MGI
  • decreased cardiac output / MGI
  • decreased circulating glycerol level / MGI
  • abnormal heart left ventricle morphology / MGI
  • abnormal ear development / MGI
  • head tossing / MGI
  • hearing/vestibular/ear phenotype / MGI
  • decreased cardiac stroke volume / MGI
  • abnormal heart left ventricle weight / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
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